He blamed in part the belief that Republicans should compromise more with Democrats for the GOP's failure to take back the White House and the Senate.
"We have to give in because if we don't we run the risk of losing the White House and not taking control of the Senate. We know how that turned out," he said.
"The leadership was too cautious, and we missed an opportunity to make a real difference," he said.
He's one potential contender for Landrieu's seat when she comes up for reelection in 2014. Though the three-term senator won reelection in 2008 with slightly more than 50 percent of the vote, Republican Mitt Romney took Louisiana by more than 15 percent this year, making it a top pickup opportunity for Senate Republicans.
The only definitive details Landry offered about his future plans included a favorite hobby: duck hunting.
"I plan to do a lot of hunting in the next month," he said.