“We have not had a confirmed administrator since 2006,” Sen. Tim KaineTim KaineMattis on rise in Trump administration Senate advances Trump's Commerce pick Steve Mnuchin, foreclosure king, now runs your US Treasury MORE (D-Va.) said ahead of the vote. “It will be a good thing for the mission and the country to confirm an administrator.”

Republican Sens. Ted CruzTed CruzTrump to interview four candidates for national security adviser Milo Yiannopoulos to speak at CPAC Reports: Petraeus off the list, Trump down to three candidates to replace Flynn MORE (Texas), Ron JohnsonRon JohnsonDems ask for hearings on Russian attempts to attack election infrastructure GOP senators unveil bill to give Congress control of consumer bureau budget GOP gets bolder in breaking with Trump MORE (Wis.), Mike LeeMike LeeTop antitrust senators call for Sessions to scrutinize AT&T-Time Warner merger Public lands dispute costs Utah a major trade show GOP senators unveil bill to give Congress control of consumer bureau budget MORE (Utah), Mike CrapoMike CrapoTime for the feds to deregulate gun suppressors Senate votes to repeal transparency rule for oil companies Live coverage of Sessions confirmation hearing MORE (Idaho), James Risch (Idaho), Mitch McConnellMitch McConnellRepublicans play clean up on Trump's foreign policy Americans brimming with optimism on the economy McCain hopes Americans can be confident GOP-controlled Congress can investigate president MORE and Rand PaulRand PaulTrump’s feud with the press in the spotlight Rand Paul: We’re very lucky John McCain’s not in charge Rand Paul: John Bolton would be a 'bad choice' for national security adviser MORE (Ky.) voted against Tavenner's nominations.

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Sen. Tom HarkinTom HarkinGrassley challenger no stranger to defying odds Clinton ally stands between Sanders and chairmanship dream Do candidates care about our health or just how much it costs? MORE (D-Iowa) had placed a hold on her nomination out of frustration with the administration’s plan to spend prevention funds on promotions for the Affordable Care Act. He lifted the hold earlier this month after he said enough light had been shined on the issue.

CMS administers the Medicare and Medicaid programs and is also charged with implementing most of Obama's healthcare law. Tavenner has been leading CMS on an acting basis.

Kaine said Tavenner, who is from Virginia, was the right pick because she would bring a patient-focused “nurse’s attitude” to CMS and she is an “expert” on finding healthcare cost savings.

Before the vote on Tavenner, the Senate also voted to approve the nomination of William Orrick to be U.S. District Judge for the Northern District of California. He was confirmed on a 56-41 vote.

Sen. Barbara BoxerBarbara BoxerCarly Fiorina 'certainly looking at' Virginia Senate run Top Obama adviser signs with Hollywood talent agency: report 
Democrats vie for chance to take on Trump as California governor MORE (D-Calif.) said she was glad Orrick got a vote because the Northern District of California has a judicial emergency with a caseload 24 percent higher than the national average.

“We all know justice delayed is justice denied,” Boxer said. “That’s why I’m excited we’re finally getting a vote on this nominee.”

Sen. Chuck GrassleyChuck GrassleyFlynn told FBI he didn't talk sanctions with Russian envoy: report Gorsuch hearing date set for March 20 Judiciary Committee wants briefing, documents on Flynn resignation MORE (R-Iowa) said he opposed Orrick's nomination because he  didn't like a judicial decision he made that maintained the “weak status quo” of immigration and border enforcement. He added that Orrick didn't answer all of his questions during his confirmation hearing with the Judiciary Committee, where Grassley serves as the ranking member.